The Potency of Kuldon® Solution in The Healing Process of Aphthous Stomatitis

Objectives: This study aimed to assess the efficacy of Kuldon® solution in the healing process of aphthous stomatitis. Methods: A double-blind randomized controlled trial was conducted involving 60 subjects (27 males, 33 females), randomly assigned to receive either Kuldon® solution (Drug A) or hyaluronic acid rinse (Drug B). Pain was evaluated using the Visual Analogue Scale (VAS), and lesion diameter was measured on days 2, 5, and 7. Data were analyzed using the Mann-Whitney test (p < 0.05). Results: Drug A showed a greater reduction in pain and lesion size compared to Drug B. By day 5, 100% of Drug A users reported no pain, with 90% showing lesion reduction.Conclusion: Kuldon® solution demonstrates significant therapeutic potential in managing aphthous stomatitis.

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Publication Details

Journal
Biology Medicine & Natural Product Chemistry
Published
2025-12-12
DOI
https://doi.org/10.14421/biomedich.2025.142.1241-1245
Primary Topic
Oral Health Pathology and Treatment
Type
article
Field-Weighted Citation Impact
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article

The Potency of Kuldon® Solution in The Healing Process of Aphthous Stomatitis

Biology Medicine & Natural Product Chemistry
Oral Health Pathology and Treatment
article

The Potency of Kuldon® Solution in The Healing Process of Aphthous Stomatitis

article en

Abstract

Objectives: This study aimed to assess the efficacy of Kuldon® solution in the healing process of aphthous stomatitis. Methods: A double-blind randomized controlled trial was conducted involving 60 subjects (27 males, 33 females), randomly assigned to receive either Kuldon® solution (Drug A) or hyaluronic acid rinse (Drug B). Pain was evaluated using the Visual Analogue Scale (VAS), and lesion diameter was measured on days 2, 5, and 7. Data were analyzed using the Mann-Whitney test (p < 0.05). Results: Drug A showed a greater reduction in pain and lesion size compared to Drug B. By day 5, 100% of Drug A users reported no pain, with 90% showing lesion reduction.Conclusion: Kuldon® solution demonstrates significant therapeutic potential in managing aphthous stomatitis.

Biology Medicine & Natural Product ChemistryVol. 14(2)
Universitas Trisakti (ID), Military Hospital (PK), 3D Technology Laboratories (United States) (US)
Good health and well-being
Openalex Percentile: Top 34%
Oral Health Pathology and Treatment
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