Advancing gene therapies for β-hemoglobinopathies with novel genome and epigenome editing tools

Charlotte Barker, Editor, BioInsights, speaks to Annarita Miccio, Group Leader, Imagine Institute of Genetic Diseases, discussing ongoing research aimed at developing gene therapies for β-hemoglobinopathies, focusing on transcriptional and epigenetic regulation. They also explore innovative tools such as CRISPR-Cas9, base editing, and epigenome editing to improve treatment safety and efficiency, with the goal of making gene therapies more accessible globally.

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Publication Details

Journal
Cell and Gene Therapy Insights
Published
2024-09-18
DOI
https://doi.org/10.18609/cgti.2024.133
Primary Topic
CRISPR and Genetic Engineering
Type
article
Field-Weighted Citation Impact
0.00
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article

Advancing gene therapies for β-hemoglobinopathies with novel genome and epigenome editing tools

Cell and Gene Therapy Insights
CRISPR and Genetic Engineering
article

Advancing gene therapies for β-hemoglobinopathies with novel genome and epigenome editing tools

article en

Abstract

Charlotte Barker, Editor, BioInsights, speaks to Annarita Miccio, Group Leader, Imagine Institute of Genetic Diseases, discussing ongoing research aimed at developing gene therapies for β-hemoglobinopathies, focusing on transcriptional and epigenetic regulation. They also explore innovative tools such as CRISPR-Cas9, base editing, and epigenome editing to improve treatment safety and efficiency, with the goal of making gene therapies more accessible globally.

Cell and Gene Therapy InsightsVol. 10(9)
Université Paris Cité (FR), Institut des Maladies Génétiques Imagine (FR)
Openalex Percentile: Top 48%
CRISPR and Genetic Engineering
DOISourceOpenAlex
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Advancing gene therapies for β-hemoglobinopathies with novel genome and epigenome editing tools · Cell and Gene Therapy Insights (2024) | TGRS Research Map | TGRS