Implementing platform-based technologies to scale viral vector manufacturing consistently and efficiently

Although advancements in viral vector manufacturing have enabled significant progress in cell and gene therapies, the field continues to face challenges in ensuring vector productivity and purity as manufacturing scales up. Abi Pinchbeck, Editor of BioInsights, speaks with Xueyuan Liu, Director of the Research Vector Core at Children’s Hospital of Philadelphia, about strategies for overcoming these challenges, including innovations in process optimization, vector design, and advanced analytical tools to enhance the clinical and commercial potential of viral vectors.

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Publication Details

Journal
Cell and Gene Therapy Insights
Published
2024-12-19
DOI
https://doi.org/10.18609/cgti.2024.183
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

Implementing platform-based technologies to scale viral vector manufacturing consistently and efficiently

Cell and Gene Therapy Insights
Virus-based gene therapy research
article

Implementing platform-based technologies to scale viral vector manufacturing consistently and efficiently

article en

Abstract

Although advancements in viral vector manufacturing have enabled significant progress in cell and gene therapies, the field continues to face challenges in ensuring vector productivity and purity as manufacturing scales up. Abi Pinchbeck, Editor of BioInsights, speaks with Xueyuan Liu, Director of the Research Vector Core at Children’s Hospital of Philadelphia, about strategies for overcoming these challenges, including innovations in process optimization, vector design, and advanced analytical tools to enhance the clinical and commercial potential of viral vectors.

Cell and Gene Therapy InsightsVol. 10(11)
Children's Hospital of Philadelphia (US)
Industry, innovation and infrastructure
Openalex Percentile: Top 32%
Virus-based gene therapy research
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