History and progress in viral vector particle size distribution analysis

Abi Pinchbeck, Editor, Cell & Gene Therapy Insights, speaks to Steven Berkowitz, Analytical Development Expert, taking a deep dive into the role of analytical ultracentrifugation (AUC) and other methods used in viral vector particle size distribution analysis. They discuss the multi-levels of heterogeneity present in gene therapy products, the history and relevance of AUC as the ‘gold standard’ of molecular characterization, and the up-and-coming tools and developments in the space.