Infiltrative Endometriosis Clinically Mimicking Ovarian Malignancy: Diagnostic Utility of Intraoperative Frozen Section

Endometriosis is a benign gynecological condition that commonly affects women of reproductive age. It is characterized by the presence of ectopic endometrial tissue, predominantly within the pelvic cavity. Ovarian endometriosis usually presents as an endometrioma with typical clinical and radiological features. However, atypical presentations such as varied symptoms, elevated tumor markers, and inconclusive imaging often complicate the differentiation between benign and malignant ovarian masses. This poses significant diagnostic challenges, which can be addressed with the use of intraoperative frozen sections. We hereby report a case of infiltrative endometriosis that presented with clinical features, radiological findings, and elevated serum tumor markers suggestive of ovarian malignancy.

Institutions

Publication Details

Journal
Cureus
Published
2025-12-14
DOI
https://doi.org/10.7759/cureus.99229
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Infiltrative Endometriosis Clinically Mimicking Ovarian Malignancy: Diagnostic Utility of Intraoperative Frozen Section

Cureus
Endometriosis Research and Treatment
article

Infiltrative Endometriosis Clinically Mimicking Ovarian Malignancy: Diagnostic Utility of Intraoperative Frozen Section

article en

Abstract

Endometriosis is a benign gynecological condition that commonly affects women of reproductive age. It is characterized by the presence of ectopic endometrial tissue, predominantly within the pelvic cavity. Ovarian endometriosis usually presents as an endometrioma with typical clinical and radiological features. However, atypical presentations such as varied symptoms, elevated tumor markers, and inconclusive imaging often complicate the differentiation between benign and malignant ovarian masses. This poses significant diagnostic challenges, which can be addressed with the use of intraoperative frozen sections. We hereby report a case of infiltrative endometriosis that presented with clinical features, radiological findings, and elevated serum tumor markers suggestive of ovarian malignancy.

CureusVol. 17(12)
Maulana Azad Medical College (IN)
Good health and well-being
Openalex Percentile: Top 29%
Endometriosis Research and Treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.