What comes first: Heart rate variability changes or insomnia? A causal investigation using Mendelian randomization
This study provides genetic evidence that altered HRV may causally increase insomnia risk, while insomnia does not appear to causally affect HRV. These findings suggest that regulating HRV might help alleviate insomnia symptoms and improve sleep quality, and highlight the potential of HRV as a therapeutic target in sleep disorders.
Institutions
- Beijing University of Chinese Medicine (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Changchun University of Chinese Medicine (CN)
Publication Details
- Journal
- International Journal of Clinical and Health Psychology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1016/j.ijchp.2025.100656
- Primary Topic
- Heart Rate Variability and Autonomic Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00