HbA1c Variability as a Predictor of Neurocognitive Decline in Children With Type 1 Diabetes

Higher HbA1c variability is significantly associated with poorer neurocognitive outcomes in children with T1DM, independent of mean HbA1c levels. Long-term glycemic stability may therefore be a crucial target to preserve cognitive function in pediatric diabetes care.

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Publication Details

Journal
Cureus
Published
2025-12-13
DOI
https://doi.org/10.7759/cureus.99141
Primary Topic
Diabetes Management and Research
Type
article
Field-Weighted Citation Impact
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article

HbA1c Variability as a Predictor of Neurocognitive Decline in Children With Type 1 Diabetes

Cureus
Diabetes Management and Research
article

HbA1c Variability as a Predictor of Neurocognitive Decline in Children With Type 1 Diabetes

article en

Abstract

Higher HbA1c variability is significantly associated with poorer neurocognitive outcomes in children with T1DM, independent of mean HbA1c levels. Long-term glycemic stability may therefore be a crucial target to preserve cognitive function in pediatric diabetes care.

CureusVol. 17(12)
University Hospitals Birmingham NHS Foundation Trust (GB), Nishtar Medical College and Hospital (PK), Thi Qar University (IQ), Punjab Medical College (PK), Khyber Teaching Hospital (PK), Combined Military Hospital (PK), Worcestershire Acute Hospitals NHS Trust (GB), Allied Hospital (PK), University Hospital and Clinics (US)
No poverty
Openalex Percentile: Top 32%
Diabetes Management and Research
DOIOpen Access PDFOpenAlex
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HbA1c Variability as a Predictor of Neurocognitive Decline in Children With Type 1 Diabetes · Cureus (2025) | TGRS Research Map | TGRS