Case report of intracranial tumor with serum MOG-IgG positivity

Serum MOG-IgG positivity and an initial response to immunotherapy may be misleading and contribute to diagnostic confusion with inflammatory demyelinating disorders. In atypical or treatment-refractory MOG antibody-associated disease, clinicians should remain vigilant for the possibility of a central nervous system space-occupying lesion.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-12-12
DOI
https://doi.org/10.3389/fimmu.2025.1673927
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Case report of intracranial tumor with serum MOG-IgG positivity

Frontiers in Immunology
Autoimmune Neurological Disorders and Treatments
article

Case report of intracranial tumor with serum MOG-IgG positivity

article en

Abstract

Serum MOG-IgG positivity and an initial response to immunotherapy may be misleading and contribute to diagnostic confusion with inflammatory demyelinating disorders. In atypical or treatment-refractory MOG antibody-associated disease, clinicians should remain vigilant for the possibility of a central nervous system space-occupying lesion.

Frontiers in ImmunologyVol. 16
Army Medical University (CN), Daping Hospital (CN), People's Liberation Army No. 150 Hospital (CN), Changchun 208 Hospital (CN)
Chongqing Science and Technology Commission, Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission
Good health and well-being
Openalex Percentile: Top 33%
Autoimmune Neurological Disorders and Treatments
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