The gut microbiome as a potential predictive biomarker for breast cancer: emerging association and geographic differences

Despite heterogeneity, converging evidence supports reduced diversity and shifts in select taxa, particularly enrichment of <i>Bacteroides</i> and depletion of <i>Faecalibacterium</i>, as emerging features of the BC microbiome. Geographic differences underscore the influence of host and environmental factors. These findings suggest biomarker potential but highlight the need for larger, longitudinal, and standardized studies to establish causality and clinical utility.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-12-12
DOI
https://doi.org/10.3389/fonc.2025.1666830
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

The gut microbiome as a potential predictive biomarker for breast cancer: emerging association and geographic differences

Frontiers in Oncology
Gut microbiota and health
article

The gut microbiome as a potential predictive biomarker for breast cancer: emerging association and geographic differences

article en

Abstract

Despite heterogeneity, converging evidence supports reduced diversity and shifts in select taxa, particularly enrichment of <i>Bacteroides</i> and depletion of <i>Faecalibacterium</i>, as emerging features of the BC microbiome. Geographic differences underscore the influence of host and environmental factors. These findings suggest biomarker potential but highlight the need for larger, longitudinal, and standardized studies to establish causality and clinical utility.

Frontiers in OncologyVol. 15
The University of Sydney (AU), Mater Health Services (AU), Royal North Shore Hospital (AU), Genesis HealthCare (US), Mater Misericordiae Hospital (AU), Cancer Institute of New South Wales (AU)
Gender equality
Openalex Percentile: Top 38%
Gut microbiota and health
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