Up-regulation of peripheral and central CGRP expression combined with subchondral bone remodeling in rat MIA-induced TMJOA model

MIA-induced rat TMJOA pain could be attributed to the augmented exprssion of CGRP in the TMJ subchondral bone, TG, TNC and hippocampus tissues. An elevated level of CGRP stimulated nociception which was implicated in the development of peripheral and central sensitization in TMJOA pain.

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Publication Details

Journal
Journal of Oral & Facial Pain and Headache
Published
2025-12-12
DOI
https://doi.org/10.22514/jofph.2025.078
Primary Topic
Temporomandibular Joint Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Up-regulation of peripheral and central CGRP expression combined with subchondral bone remodeling in rat MIA-induced TMJOA model

Journal of Oral & Facial Pain and Headache
Temporomandibular Joint Disorders
article

Up-regulation of peripheral and central CGRP expression combined with subchondral bone remodeling in rat MIA-induced TMJOA model

article en

Abstract

MIA-induced rat TMJOA pain could be attributed to the augmented exprssion of CGRP in the TMJ subchondral bone, TG, TNC and hippocampus tissues. An elevated level of CGRP stimulated nociception which was implicated in the development of peripheral and central sensitization in TMJOA pain.

Journal of Oral & Facial Pain and HeadacheVol. 39(4)
University of Dental Medicine (MM), State Key Laboratory of Oral Diseases
Openalex Percentile: Top 32%
Temporomandibular Joint Disorders
DOIOpen Access PDFOpenAlex
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Up-regulation of peripheral and central CGRP expression combined with subchondral bone remodeling in rat MIA-induced TMJOA model · Journal of Oral & Facial Pain and Headache (2025) | TGRS Research Map | TGRS