Multiplex PCR for lower respiratory tract infection diagnosis in ICU and non-ICU settings: enhancing diagnostic stewardship in Indian tertiary care

The BioFire FilmArray Pneumonia Panel (BFPP) demonstrated high diagnostic sensitivity of 94.6% and detected pathogens in 81.7% of suspected LRTI cases, compared to 44.2% positivity by conventional culture. BFPP identified 69 additional pathogens missed by culture, enabling earlier targeted therapy and improved diagnostic stewardship in ICU and non-ICU settings.

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Publication Details

Journal
Iranian Journal of Microbiology
Published
2025-12-12
DOI
https://doi.org/10.18502/ijm.v17i6.20360
Primary Topic
Nosocomial Infections in ICU
Type
article
Field-Weighted Citation Impact
0.00
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article

Multiplex PCR for lower respiratory tract infection diagnosis in ICU and non-ICU settings: enhancing diagnostic stewardship in Indian tertiary care

Iranian Journal of Microbiology
Nosocomial Infections in ICU
article

Multiplex PCR for lower respiratory tract infection diagnosis in ICU and non-ICU settings: enhancing diagnostic stewardship in Indian tertiary care

article en

Abstract

The BioFire FilmArray Pneumonia Panel (BFPP) demonstrated high diagnostic sensitivity of 94.6% and detected pathogens in 81.7% of suspected LRTI cases, compared to 44.2% positivity by conventional culture. BFPP identified 69 additional pathogens missed by culture, enabling earlier targeted therapy and improved diagnostic stewardship in ICU and non-ICU settings.

Iranian Journal of MicrobiologyVol. 17(6)
Swami Rama Himalayan University (IN), All India Institute of Medical Sciences Rishikesh (IN)
Good health and well-being
Openalex Percentile: Top 35%
Nosocomial Infections in ICU
DOIOpen Access PDFOpenAlex
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Multiplex PCR for lower respiratory tract infection diagnosis in ICU and non-ICU settings: enhancing diagnostic stewardship in Indian tertiary care · Iranian Journal of Microbiology (2025) | TGRS Research Map | TGRS