MARZ AKYAS KHUSYAT-UR-RAHIM (POLYCYSTIC OVARIAN SYNDROME): AN INTEGRATIVE ANALYSIS FROM UNANI PERSPECTIVE AND MODERN MEDICINE

Polycystic Ovary Syndrome (PCOS) Marz Akyas Khusyat-ur-Rahim is one of the most common endocrine and metabolic disorders affecting women of reproductive age, with a global prevalence estimated to range between 6% and 20%, depending on the diagnostic criteria and population studied. It is characterized by chronic anovulation, hyperandrogenism and polycystic ovarian morphology. PCOS is frequently associated with obesity, insulin resistance, menstrual irregularities, infertility, increased risk of type 2 diabetes and cardiovascular diseases. While modern medicine explains PCOS in terms of hormonal imbalance, altered gonadotropin secretion and metabolic dysfunction, Unani medicine interpret the condition through disturbances in Mizaj (temperament), imbalance of Akhlat (humours) and dysfunction of Quwā Tabi’iyya and Quwwat-e-Mudabbira. This paper aims to explore PCOS from an integrative perspective by correlating contemporary physiological mechanisms with classical Unani concepts. It highlights similarities in the understanding of etiopathogenesis, clinical manifestations, and progression of the disorder. By bridging modern science with Unani theoretical frameworks, this study offers a more holistic interpretation of PCOS, emphasizing individualized temperament-based management strategies. The findings suggest that combining modern diagnostic protocols with Unani principles of balance restoration, diet modulation and lifestyle correction may enhance therapeutic outcomes.