Beyond CRISPR: TALEN, smart cells, and the regulatory edge in gene editing

“Success in gene editing is not only about having strong backbones or optimizing specificity, it is also about delivering these tools in a way that ensures performance and precision.”In this discussion, Abi Pinchbeck, Editor, Cell & Gene Therapy Insights, speaks to David Sourdive, Executive Vice President, CMC & Manufacturing, Cellectis, who shares insights into the company’s pioneering work in gene editing and allogeneic CAR-T cell therapies. With considerations surrounding the regulatory CMC space, they explore how smart cell innovation is shaping the future of gene editing.

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Publication Details

Journal
Cell and Gene Therapy Insights
Published
2025-09-09
DOI
https://doi.org/10.18609/cgti.2025.091
Primary Topic
CRISPR and Genetic Engineering
Type
article
Field-Weighted Citation Impact
0.00
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article

Beyond CRISPR: TALEN, smart cells, and the regulatory edge in gene editing

Cell and Gene Therapy Insights
CRISPR and Genetic Engineering
article

Beyond CRISPR: TALEN, smart cells, and the regulatory edge in gene editing

article en

Abstract

“Success in gene editing is not only about having strong backbones or optimizing specificity, it is also about delivering these tools in a way that ensures performance and precision.”In this discussion, Abi Pinchbeck, Editor, Cell & Gene Therapy Insights, speaks to David Sourdive, Executive Vice President, CMC & Manufacturing, Cellectis, who shares insights into the company’s pioneering work in gene editing and allogeneic CAR-T cell therapies. With considerations surrounding the regulatory CMC space, they explore how smart cell innovation is shaping the future of gene editing.

Cell and Gene Therapy InsightsVol. 11(7)
Laboratoire de Biologie Moléculaire et Cellulaire des Eucaryotes (FR)
Industry, innovation and infrastructure
Openalex Percentile: Top 38%
CRISPR and Genetic Engineering
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