Comparative Study of Antimicrobial Action of Aloe vera and Garlic Against Candidal Albicans in Clinical Isolates

Candida albicans is an opportunistic fungal pathogen that commonly causes infections in humans, particularly in immunocompromised individuals. It is responsible for various infections, including oral thrush, vaginal candidiasis, and systemic candidiasis with mortality rate of 25-60% in systemic candidemia Herbal drugs have found wide spread use in many countries because they are easily, available, cheaper, and safer than synthetics drug (Wanjari & Wanjari, 2019). According to World Health Organization (WHO) about 80% of people worldwide are currently depending on traditional medicine for their primary health care needs. The aim of our study was to compare the antimicrobial efficacy of garlic (Allium Sativum) and Aloe vera (Aloe barbadensis millar) extracts against Candida albicans. Zones of inhibition were measured in millimeters to determine antifungal activity. It is concluded that garlic extract is more effective than aloe vera in inhibiting the grow of Candida alblicans.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-12-31
DOI
https://doi.org/10.5281/zenodo.17875050
Primary Topic
Phytochemistry and biological activity of medicinal plants
Type
article
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article

Comparative Study of Antimicrobial Action of Aloe vera and Garlic Against Candidal Albicans in Clinical Isolates

Zenodo (CERN European Organization for Nuclear Research)
Phytochemistry and biological activity of medicinal plants
article

Comparative Study of Antimicrobial Action of Aloe vera and Garlic Against Candidal Albicans in Clinical Isolates

article en

Abstract

Candida albicans is an opportunistic fungal pathogen that commonly causes infections in humans, particularly in immunocompromised individuals. It is responsible for various infections, including oral thrush, vaginal candidiasis, and systemic candidiasis with mortality rate of 25-60% in systemic candidemia Herbal drugs have found wide spread use in many countries because they are easily, available, cheaper, and safer than synthetics drug (Wanjari & Wanjari, 2019). According to World Health Organization (WHO) about 80% of people worldwide are currently depending on traditional medicine for their primary health care needs. The aim of our study was to compare the antimicrobial efficacy of garlic (Allium Sativum) and Aloe vera (Aloe barbadensis millar) extracts against Candida albicans. Zones of inhibition were measured in millimeters to determine antifungal activity. It is concluded that garlic extract is more effective than aloe vera in inhibiting the grow of Candida alblicans.

Zenodo (CERN European Organization for Nuclear Research)
Lagos State University (NG), Ajayi Crowther University (NG), University of Ilorin Teaching Hospital (NG), Lead City University (NG)
Good health and well-being
Openalex Percentile: Top 26%
Phytochemistry and biological activity of medicinal plants
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