Leucine-rich repeat neuronal 1 as a prognostic indicator and functional modulator in breast cancer

Overall, LRRN1 emerges as a promising prognostic indicator and functional mediator in advanced breast cancer. It potentially exerts its effects by influencing the Wnt signaling pathway and regulating immunotherapy responses. However, the specific mechanisms underlying LRRN1's actions, as well as its potential clinical applications, still require further exploration to fully translate these findings into clinical practice for advanced breast cancer treatment.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-12-11
DOI
https://doi.org/10.3389/fonc.2025.1724785
Primary Topic
Clusterin in disease pathology
Type
article
Field-Weighted Citation Impact
0.00
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article

Leucine-rich repeat neuronal 1 as a prognostic indicator and functional modulator in breast cancer

Frontiers in Oncology
Clusterin in disease pathology
article

Leucine-rich repeat neuronal 1 as a prognostic indicator and functional modulator in breast cancer

article en

Abstract

Overall, LRRN1 emerges as a promising prognostic indicator and functional mediator in advanced breast cancer. It potentially exerts its effects by influencing the Wnt signaling pathway and regulating immunotherapy responses. However, the specific mechanisms underlying LRRN1's actions, as well as its potential clinical applications, still require further exploration to fully translate these findings into clinical practice for advanced breast cancer treatment.

Frontiers in OncologyVol. 15
Qingdao University (CN), Tongji University (CN), Affiliated Hospital of Qingdao University (CN)
Good health and well-being
Openalex Percentile: Top 33%
Clusterin in disease pathology
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