Leucine-rich repeat neuronal 1 as a prognostic indicator and functional modulator in breast cancer
Overall, LRRN1 emerges as a promising prognostic indicator and functional mediator in advanced breast cancer. It potentially exerts its effects by influencing the Wnt signaling pathway and regulating immunotherapy responses. However, the specific mechanisms underlying LRRN1's actions, as well as its potential clinical applications, still require further exploration to fully translate these findings into clinical practice for advanced breast cancer treatment.
Institutions
- Qingdao University (CN)
- Tongji University (CN)
- Affiliated Hospital of Qingdao University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-12-11
- DOI
- https://doi.org/10.3389/fonc.2025.1724785
- Primary Topic
- Clusterin in disease pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00