Assessment of Blood Parameters, Glycosylated Fibronectin (GF) Biomarker, and BMI in Pregnant Women Undergoing Hysterectomy

Background: Hysterectomy is a critical intervention in obstetric emergencies such as postpartum hemorrhage and placenta accreta, conditions that may be influenced by maternal characteristics. Objective: To evaluate the association between maternal age, cesarean section history, blood parameters, glycosylated fibronectin (GF), and body mass index (BMI) in women undergoing hysterectomy. Methods: Seventy women (22–42 years) undergoing hysterectomy were categorized into hemorrhage and placenta accreta subgroups. Twenty women with vaginal deliveries served as controls. Parameters, including GF (via ELISA), CBC, PT, PTT, INR, and BMI, were analyzed. Results: BMI and GF levels were significantly altered in hysterectomy groups, especially in placenta accreta cases. CBC showed reduced RBC and hemoglobin, with increased granulocytes and platelets. Elevated BMI correlated with granulocyte percentage in older patients. Conclusion: GF shows potential as a biomarker for pregnancy-related hysterectomy. High BMI and prior cesarean deliveries may increase the risk of complications leading to hysterectomy.