Development of antiaging cream based on pegagan and moringa nanoparticles to produce halaland green cosmetics (sertifikat hak cipta)

The general objective of this study was to develop an antiaging cream made from pegagan (C. asiatica) and moringa (M. oliefera) nanoparticles using a process that considers the principles of halal and toyyib and is environmentally friendly in an effort to produce halal cosmetic products in Indonesia. This study took 2 years. The first year of research was the formulation and characterization of antiaging cream nanoparticles combination of pegagan and moringa in vitro. This type of research is experimental. This study used a green extraction method consisting of Pulse Electric Field (PEF) as a pre-treatment with a combination extraction method of Microwave-Ultrasonic Assisted Extraction (MUAE). Synthesis of silver nanoparticles using a combination of pegagan and moringa bioreductors. This study used 4 formulations of variations in the concentration of pegagan and moringa nanoparticle combinations with 4 repetitions, namely F1 (0%), F2 (5%), F3 (10%) and F4 (20%). Testing of the physical characteristics of the cream formulation included organoleptic tests, stability tests, pH tests, spreadability tests, and viscosity tests. Irritation test was conducted on 8 volunteers. Biochemical character measurement in the form of antioxidant activity and SPF measurement with UV-Vis spectrophotometer. Total microbial evaluation using Total Plate Count (TPC) method. and cream stability test was conducted for 1 month. Quantitative data will be tested for normality and homogeneity then analyzed using 1-way ANOVA if there is a significant difference then a further Duncan Multiple Range Test (DMRT) 5% test is carried out while qualitative data is analyzed descriptively then presented in the form of tables, pictures and graphs.