Widening access to penicillin allergy assessment in the United Kingdom – a proposed implementation plan for the National Health Service (NHS)

Globally, there is increasing evidence that incorrect penicillin allergy labels negatively impact patient outcomes, antibiotic prescribing and antimicrobial resistance, leading to growing concern about this patient safety issue and how to resolve it. While many millions of patients worldwide have incorrect penicillin allergy labels, there are too few specialist allergists and a lack of 'point-of-care' tests to address this problem. Numerous research studies now provide evidence of the feasibility and importance of widening access to penicillin allergy assessment. Researchers from two UK-based studies (SPACE and ALABAMA), in collaboration with key stakeholders including patient representatives, gave their views to shape a high-level implementation plan to facilitate widening access to penicillin allergy assessment in the UK. This viewpoint describes the basis of the implementation plan and summarises the key actions required for successful delivery. Whilst the plan is intended for the UK, we hope to promote international shared learning and collaboration to address this global problem informed by the UK context.

Publication Details

Journal
Research Portal (King's College London)
Published
2025-11-14
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
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article

Widening access to penicillin allergy assessment in the United Kingdom – a proposed implementation plan for the National Health Service (NHS)

Research Portal (King's College London)
Drug-Induced Adverse Reactions
article

Widening access to penicillin allergy assessment in the United Kingdom – a proposed implementation plan for the National Health Service (NHS)

article en

Abstract

Globally, there is increasing evidence that incorrect penicillin allergy labels negatively impact patient outcomes, antibiotic prescribing and antimicrobial resistance, leading to growing concern about this patient safety issue and how to resolve it. While many millions of patients worldwide have incorrect penicillin allergy labels, there are too few specialist allergists and a lack of 'point-of-care' tests to address this problem. Numerous research studies now provide evidence of the feasibility and importance of widening access to penicillin allergy assessment. Researchers from two UK-based studies (SPACE and ALABAMA), in collaboration with key stakeholders including patient representatives, gave their views to shape a high-level implementation plan to facilitate widening access to penicillin allergy assessment in the UK. This viewpoint describes the basis of the implementation plan and summarises the key actions required for successful delivery. Whilst the plan is intended for the UK, we hope to promote international shared learning and collaboration to address this global problem informed by the UK context.

Research Portal (King's College London)
Partnerships for the goals
Openalex Percentile: Top 33%
Drug-Induced Adverse Reactions
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