Metástases Retroperitoneais de Carcinoma Lobular da Mama: Um Relato de Caso

This is a case report of a 50-year-old woman with bilateral lobular breast carcinoma. Staging imaging revealed diffuse thickening of the retroperitoneal fasciae, involving both renal hila and resulting in bilateral hydronephrosis, as seen in MRI. along with metastatic bone involvement. Notably, FDG-PET-CT showed no increased metabolic activity in the retroperitoneum.  Because of the indeterminate nature of the retroperitoneal thickening, an ultrasound-guided biopsy of the retroperitoneal thickening was performed, which confirmed metastatic involvement by invasive lobular carcinoma. The literature demonstrates that lobular carcinoma has a higher propensity to metastasize to the peritoneum, retroperitoneum and gastrointestinal tract, compared to invasive ductal carcinoma. This case report highlights the importance of the clinical manifestations and subtle radiological findings of peritoneal and retroperitoneal spread of ILC.

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Publication Details

Journal
Scientific Repository of Open Access of Portugal (RCAAP)
Published
2025-11-19
Primary Topic
Intraperitoneal and Appendiceal Malignancies
Type
article
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article

Metástases Retroperitoneais de Carcinoma Lobular da Mama: Um Relato de Caso

Scientific Repository of Open Access of Portugal (RCAAP)
Intraperitoneal and Appendiceal Malignancies
article

Metástases Retroperitoneais de Carcinoma Lobular da Mama: Um Relato de Caso

article en

Abstract

This is a case report of a 50-year-old woman with bilateral lobular breast carcinoma. Staging imaging revealed diffuse thickening of the retroperitoneal fasciae, involving both renal hila and resulting in bilateral hydronephrosis, as seen in MRI. along with metastatic bone involvement. Notably, FDG-PET-CT showed no increased metabolic activity in the retroperitoneum.  Because of the indeterminate nature of the retroperitoneal thickening, an ultrasound-guided biopsy of the retroperitoneal thickening was performed, which confirmed metastatic involvement by invasive lobular carcinoma. The literature demonstrates that lobular carcinoma has a higher propensity to metastasize to the peritoneum, retroperitoneum and gastrointestinal tract, compared to invasive ductal carcinoma. This case report highlights the importance of the clinical manifestations and subtle radiological findings of peritoneal and retroperitoneal spread of ILC.

Scientific Repository of Open Access of Portugal (RCAAP)
Instituto Português de Oncologia de Coimbra Francisco Gentil (PT), Instituto Português de Oncologia de Coimbra Francisco Gentil (PT)
Good health and well-being
Openalex Percentile: Top 29%
Intraperitoneal and Appendiceal Malignancies
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