a gene therapy-directed and metabolism-based strategy to impair glioblastoma (GBM)

Funding Information: This work benefited from access to CERMAX, ITQB-NOVA, Oeiras, Portugal with equipment funded by FCT, project AAC 01/SAICT/2016. Funding Information: The institutions are funded by Funda\u00E7\u00E3o para a Ci\u00EAncia e a Tecnologia/Minist\u00E9rio da Ci\u00EAncia, Tecnologia e Ensino Superior (FCT/MCTES, Portugal) through national funds to iNOVA4Health (UIDB/04462/2020 and UIDP/04462/2020), to MOSTMICRO-ITQB (UIDB/04612/2020 and UIDP/04612/2020), to BioISI (Center Grant doi 10.54499/UIDB/04046/2020), and the Associated Laboratory LS4FUTURE (LA/P/0087/2020). Filipa Martins was funded by a FCT individual Ph.D. fellowship (2020.04780.BD). Luis G. Gon\u00E7alves was financed by a FCT contract according to DL57/2016, [SFRH/BPD/111100/2015]. Data availability in a public repository is supported by NIH U2C-DK119886 and OT2-OD030544 grants. Publisher Copyright: © The Author(s), under exclusive licence to Springer Nature America, Inc. 2025.