Inflammatory Fibroid Polyp: A Rare Cause of Ileo-ileal Intussusception in Adolescents-Case Report and Review of Literature

Inflammatory fibroid polyp (IFP) of the gastrointestinal tract (GIT) is a rare benign polypoidal mesenchymal tumor. It most often affects middle-aged adults with a variable clinical presentation. The most common site is the stomach, followed by the small intestine. We report a case of a 16-year-old male who presented with the classical features of intussusception. Surgical resection of the ileocecal region revealed a pedunculated polypoidal mass. Histopathological examination showed a submucosal tumor with an onion-skin appearance comprising spindle cells, loose stroma, and mixed inflammatory infiltrate, predominantly eosinophils. IFP should be considered in the differential diagnosis even in pediatric patients with intestinal obstruction because of its bearing on management.

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Publication Details

Journal
Annals of Pathology and Laboratory Medicine
Published
2025-07-30
DOI
https://doi.org/10.21276/apalm.3575
Primary Topic
Gastrointestinal disorders and treatments
Type
article
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article

Inflammatory Fibroid Polyp: A Rare Cause of Ileo-ileal Intussusception in Adolescents-Case Report and Review of Literature

Annals of Pathology and Laboratory Medicine
Gastrointestinal disorders and treatments
article

Inflammatory Fibroid Polyp: A Rare Cause of Ileo-ileal Intussusception in Adolescents-Case Report and Review of Literature

article en

Abstract

Inflammatory fibroid polyp (IFP) of the gastrointestinal tract (GIT) is a rare benign polypoidal mesenchymal tumor. It most often affects middle-aged adults with a variable clinical presentation. The most common site is the stomach, followed by the small intestine. We report a case of a 16-year-old male who presented with the classical features of intussusception. Surgical resection of the ileocecal region revealed a pedunculated polypoidal mass. Histopathological examination showed a submucosal tumor with an onion-skin appearance comprising spindle cells, loose stroma, and mixed inflammatory infiltrate, predominantly eosinophils. IFP should be considered in the differential diagnosis even in pediatric patients with intestinal obstruction because of its bearing on management.

Annals of Pathology and Laboratory MedicineVol. 12(7)
Kalpana Chawla Government Medical College and Hospital (IN)
Good health and well-being
Openalex Percentile: Top 29%
Gastrointestinal disorders and treatments
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Inflammatory Fibroid Polyp: A Rare Cause of Ileo-ileal Intussusception in Adolescents-Case Report and Review of Literature · Annals of Pathology and Laboratory Medicine (2025) | TGRS Research Map | TGRS