Clear Cell Carcinoma of Ovary: A Rare Clinico-Pathological Entity

Clear cell carcinoma of ovary is rare neoplasm and has varied clinical manifestations. Mean age at presentation is between 40-70 years. We report a case of a 53 year old female who presented with complaints of of pain, lower abdomen. Imaging revealed a large ovarian mass with multiple metastatic deposits at presentation. Morphology and IHC favored a diagnosis of Clear cell carcinoma of left ovary. This case is presented for its rarity, varied histomorphology, morphological overlap with the commoner serous carcinoma of Ovary and and its poor response to conventional chemotherapy.

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Publication Details

Journal
Annals of Pathology and Laboratory Medicine
Published
2025-11-20
DOI
https://doi.org/10.21276/apalm.3534
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
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article

Clear Cell Carcinoma of Ovary: A Rare Clinico-Pathological Entity

Annals of Pathology and Laboratory Medicine
Ovarian cancer diagnosis and treatment
article

Clear Cell Carcinoma of Ovary: A Rare Clinico-Pathological Entity

article en

Abstract

Clear cell carcinoma of ovary is rare neoplasm and has varied clinical manifestations. Mean age at presentation is between 40-70 years. We report a case of a 53 year old female who presented with complaints of of pain, lower abdomen. Imaging revealed a large ovarian mass with multiple metastatic deposits at presentation. Morphology and IHC favored a diagnosis of Clear cell carcinoma of left ovary. This case is presented for its rarity, varied histomorphology, morphological overlap with the commoner serous carcinoma of Ovary and and its poor response to conventional chemotherapy.

Annals of Pathology and Laboratory MedicineVol. 12(11)
INHS Asvini (IN)
No poverty
Openalex Percentile: Top 32%
Ovarian cancer diagnosis and treatment
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Clear Cell Carcinoma of Ovary: A Rare Clinico-Pathological Entity · Annals of Pathology and Laboratory Medicine (2025) | TGRS Research Map | TGRS