The role of nursing-led support in the successful management of alcohol-related acute pancreatitis: A case report utilizing conservative treatment and continuous renal replacement therapy with an adsorptive Oxiris filter

Acute pancreatitis (AP) is a serious and potentially life-threatening condition characterized by inflammation of the pancreas, commonly linked to chronic alcohol consumption. The condition may arise from obstruction of the small pancreatic ducts or from the autodigestion of pancreatic tissue by its own enzymes. Additionally, toxic by-products of alcohol metabolism within the pancreas can contribute to cellular membrane damage, further exacerbating the inflammatory response. This case report presents the successful management of a 32-year-old male patient diagnosed with alcohol-related AP, who was admitted in critical condition for a period of 3 weeks to a hepatology hospital. The patient was treated conservatively with continuous renal replacement therapy (CRRT) utilizing the Oxiris filter, alongside comprehensive medical and nursing care. The Oxiris filter, known for its adsorption capabilities to remove endotoxins and inflammatory mediators, proved to be a valuable adjunct in managing the systemic inflammatory response. Nursing care played a pivotal role in the patient’s recovery, with focused interventions for tracheostomy management, hyperpyrexia control, ventilator support, and assistance with activities of daily living (ADLs). The patient was discharged in 22 days from the hospital, with no functional dysfunction. Decannulation of the tracheostomy was done on the 10 th day of management in the intensive care unit (ICU). Serum amylase and white blood cell values were normal at the time of discharge. This case highlights the importance of integrated, multidisciplinary care, particularly the critical contribution of skilled nursing, in the successful outcome of complex, critical care cases involving AP.