Photonic pathways toward real-time tissue assessment

Photonics is transforming pathology by enabling fast, label-free tissue diagnostics. We developed Higher Harmonic Generation Microscopy (HHGM), a compact femtosecond-laser platform combining SHG, THG, and autofluorescence to image unprocessed tissue with submicron resolution. HHGM reproduces histological architecture within minutes, preserves tissue for further analysis, and enables AI-driven, real-time diagnostics across cancer types.

Publication Details

Journal
Springer Link (Chiba Institute of Technology)
Published
2025-11-28
DOI
https://doi.org/10.1051/photon/202513430/pdf
Primary Topic
Advanced Fluorescence Microscopy Techniques
Type
article
Field-Weighted Citation Impact
0.00
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article

Photonic pathways toward real-time tissue assessment

Springer Link (Chiba Institute of Technology)
Advanced Fluorescence Microscopy Techniques
article

Photonic pathways toward real-time tissue assessment

article en

Abstract

Photonics is transforming pathology by enabling fast, label-free tissue diagnostics. We developed Higher Harmonic Generation Microscopy (HHGM), a compact femtosecond-laser platform combining SHG, THG, and autofluorescence to image unprocessed tissue with submicron resolution. HHGM reproduces histological architecture within minutes, preserves tissue for further analysis, and enables AI-driven, real-time diagnostics across cancer types.

Springer Link (Chiba Institute of Technology)
Openalex Percentile: Top 26%
Advanced Fluorescence Microscopy Techniques
DOISourceOpenAlex
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Photonic pathways toward real-time tissue assessment · Springer Link (Chiba Institute of Technology) (2025) | TGRS Research Map | TGRS