Adenoid Cystic Carcinoma of the Upper Eyelid: A Rare Case Report

Adenoid cystic carcinoma is a sporadic, locally aggressive, and highly recurrent malignant epithelial tumor accounting for 1% of all head and neck cancers. It primarily affects minor and major salivary glands and has a high tendency of local invasion and distant metastasis. It uncommonly originates from the palpebral portion of the lacrimal gland in the orbit. In this case report, we present a 30-year-old female patient who complained of a painless nodule in the left upper eyelid, which initially was of pea size; over time, the swelling increased to the present size. The swelling was then excised and sent for histopathological examination. Histopathological examination revealed tumor cells arranged in cribriform and tubular patterns, and finally, the diagnosis of Adenoid cystic carcinoma was made.

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Publication Details

Journal
Annals of Pathology and Laboratory Medicine
Published
2025-11-20
DOI
https://doi.org/10.21276/apalm.3588
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
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article

Adenoid Cystic Carcinoma of the Upper Eyelid: A Rare Case Report

Annals of Pathology and Laboratory Medicine
Salivary Gland Tumors Diagnosis and Treatment
article

Adenoid Cystic Carcinoma of the Upper Eyelid: A Rare Case Report

article en

Abstract

Adenoid cystic carcinoma is a sporadic, locally aggressive, and highly recurrent malignant epithelial tumor accounting for 1% of all head and neck cancers. It primarily affects minor and major salivary glands and has a high tendency of local invasion and distant metastasis. It uncommonly originates from the palpebral portion of the lacrimal gland in the orbit. In this case report, we present a 30-year-old female patient who complained of a painless nodule in the left upper eyelid, which initially was of pea size; over time, the swelling increased to the present size. The swelling was then excised and sent for histopathological examination. Histopathological examination revealed tumor cells arranged in cribriform and tubular patterns, and finally, the diagnosis of Adenoid cystic carcinoma was made.

Annals of Pathology and Laboratory MedicineVol. 12(11)
Jawaharlal Nehru Medical College Hospital (IN)
Good health and well-being
Openalex Percentile: Top 30%
Salivary Gland Tumors Diagnosis and Treatment
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