Thyroid Disease and Its Varied Presentations: A Series of Unusual Cases, a Tertiary Centre Experience

Introduction: Thyroid diseases, both non-neoplastic processes and neoplasms, are on the rise nowadays and are associated with a preponderance in females. Methods: This is a prospective study of nine (9) unusual cases of thyroid lesions conducted from January 2021 to June 2022, over one and a half years, in our tertiary care centre. Results: The age range was 22 to 75 years. All the cases were females. The different histological subtypes included haemangioma, Riedel’s thyroiditis, hyalinising trabecular tumour, anaplastic carcinoma of the thyroid, sclerosing mucoepidermoid carcinoma with eosinophilia, mucoepidermoid carcinoma, metastatic neoplasms, medullary carcinoma of the thyroid (MTC), and follicular carcinoma. Conclusion: Here we present nine (9) rare cases of the thyroid gland, ranging from benign lesions to aggressive carcinomas, such as anaplastic as well as metastatic carcinomas. Among these, hyalinising trabecular tumour and haemangioma were found to be associated with better prognosis, whereas anaplastic carcinoma and the secondaries had the worst outcomes. The prognosis of MTC and follicular carcinoma varies depending on the subtypes and other clinical variables.