Paraneoplastic renal tubular acidosis secondary to ovarian teratoma

Background: Renal tubular acidosis (RTA) is a relatively uncommon disorder, often linked to autoimmune conditions or adverse effects of certain medications. It is rare for clinicians to encounter this disorder during their medical practice. There are 3 distinct types: type 1(distal), type 2 (proximal), and type 4 (hypoaldosteronism). Etiology of a specific case of RTA can be difficult to pin, which is what prompted us to get further imaging. Our case report is going to reveal a rare relationship between RTA and an ovarian teratoma. Ovarian teratomas are a type of germ cell tumor that are composed of somatic tissue, typically ectoderm, endoderm, and mesoderm. These tissues are foreign to the anatomic site they are found in. More than 95% of ovarian teratomas are mature cystic teratomas which are generally asymptomatic. If symptoms do occur, they are typically associated with the size of the teratoma itself.

Publication Details

Journal
SHAREOK (University of Oklahoma; Oklahoma State University; Central Oklahoma University)
Published
2025-02-14
Primary Topic
Ion Transport and Channel Regulation
Type
article
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article

Paraneoplastic renal tubular acidosis secondary to ovarian teratoma

SHAREOK (University of Oklahoma; Oklahoma State University; Central Oklahoma University)
Ion Transport and Channel Regulation
article

Paraneoplastic renal tubular acidosis secondary to ovarian teratoma

article en

Abstract

Background: Renal tubular acidosis (RTA) is a relatively uncommon disorder, often linked to autoimmune conditions or adverse effects of certain medications. It is rare for clinicians to encounter this disorder during their medical practice. There are 3 distinct types: type 1(distal), type 2 (proximal), and type 4 (hypoaldosteronism). Etiology of a specific case of RTA can be difficult to pin, which is what prompted us to get further imaging. Our case report is going to reveal a rare relationship between RTA and an ovarian teratoma. Ovarian teratomas are a type of germ cell tumor that are composed of somatic tissue, typically ectoderm, endoderm, and mesoderm. These tissues are foreign to the anatomic site they are found in. More than 95% of ovarian teratomas are mature cystic teratomas which are generally asymptomatic. If symptoms do occur, they are typically associated with the size of the teratoma itself.

SHAREOK (University of Oklahoma; Oklahoma State University; Central Oklahoma University)
Good health and well-being
Openalex Percentile: Top 41%
Ion Transport and Channel Regulation
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