Bone protection in estrogen-treated rats versus oil-treated rats: An exploratory microarray analysis

Introduction/Objectives: As aging and menopause occur, a decrease in estrogen leads to a variety of physiologic changes. Bone maintenance is one of the major factors effected by decreased estrogen. Using an exploratory microarray analysis, we examined the arcuate nucleus (ARC) of the hypothalamus in estrogen-treated and oil-treated rats to identify differences in estrogen-related gene expression.