Integrated Therapeutic Approach Combining Acacia Nilotica and Modern Veterinary Practices for Foot-And-Mouth Disease in Smallholder Herds

The foot and Mouth Disease (FMD) is considered as one of the most virulently transmittable and economically disastrous viral pathogens to afflict livestock throughout the world and significantly to the small holder community of farming households like those in the Layyah district of southern Punjab, Pakistan. The paper critically analyses the FMD virus and identifies the genome structure, antigenic variations of the seven serotypes, and immunologic evasion of the virus, which makes it difficult to control. The analysis of epidemiological factors contributing to outbreaks in Layyah, such as the pattern in the movement of the animals, low levels of coverage in vaccination, and community grazing, will place the morbidity rates experienced in the area in context. The paper also discusses existing veterinary treatment measures used in controlling the outbreaks including use of antibiotics prophylaxis to prevent secondary infections, use of anti-inflammatories and metabolic support to animals ailing. It also performs a phytochemical composition of Acacia nilotica bark, which contains some bioactive compounds: phenolic acid, flavonoids, pentacyclic triterpenes, which have the qualities of antioxidants, antimicrobial microorganims, and anti-inflammatory, whose potential complementary therapeutic effects can be of interest. An interplay among the local epidemiological knowledge, development in vaccine technology, and phytochemical research will give a comprehensive understanding of FMD control measures. Results underline the imperativeness of the ideas of better immunization practices, increased information moral to the farmers, and the additional approval of phytotherapies as the only methods to counterbalance the burden of the disease in the involved territories.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-12-07
DOI
https://doi.org/10.5281/zenodo.17848672
Primary Topic
Animal Disease Management and Epidemiology
Type
article
Field-Weighted Citation Impact
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article

Integrated Therapeutic Approach Combining Acacia Nilotica and Modern Veterinary Practices for Foot-And-Mouth Disease in Smallholder Herds

Zenodo (CERN European Organization for Nuclear Research)
Animal Disease Management and Epidemiology
article

Integrated Therapeutic Approach Combining Acacia Nilotica and Modern Veterinary Practices for Foot-And-Mouth Disease in Smallholder Herds

article en

Abstract

The foot and Mouth Disease (FMD) is considered as one of the most virulently transmittable and economically disastrous viral pathogens to afflict livestock throughout the world and significantly to the small holder community of farming households like those in the Layyah district of southern Punjab, Pakistan. The paper critically analyses the FMD virus and identifies the genome structure, antigenic variations of the seven serotypes, and immunologic evasion of the virus, which makes it difficult to control. The analysis of epidemiological factors contributing to outbreaks in Layyah, such as the pattern in the movement of the animals, low levels of coverage in vaccination, and community grazing, will place the morbidity rates experienced in the area in context. The paper also discusses existing veterinary treatment measures used in controlling the outbreaks including use of antibiotics prophylaxis to prevent secondary infections, use of anti-inflammatories and metabolic support to animals ailing. It also performs a phytochemical composition of Acacia nilotica bark, which contains some bioactive compounds: phenolic acid, flavonoids, pentacyclic triterpenes, which have the qualities of antioxidants, antimicrobial microorganims, and anti-inflammatory, whose potential complementary therapeutic effects can be of interest. An interplay among the local epidemiological knowledge, development in vaccine technology, and phytochemical research will give a comprehensive understanding of FMD control measures. Results underline the imperativeness of the ideas of better immunization practices, increased information moral to the farmers, and the additional approval of phytotherapies as the only methods to counterbalance the burden of the disease in the involved territories.

Zenodo (CERN European Organization for Nuclear Research)
University of Surabaya (ID), University of the Punjab (PK), University of Agriculture Faisalabad (PK)
Good health and well-being
Openalex Percentile: Top 35%
Animal Disease Management and Epidemiology
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