Post-Infectious Acute Transverse Myelitis in a COVID-19 Patient

A 41-year-old man with no comorbidities presented with features consistent with a subacute partial upper thoracic myelopathy, two days after treatment in the emergency department for acute urinary retention. On examination, he was ambulatory but had an unsteady gait and lower limb weakness, with brisk reflexes, upgoing plantars, and subtle sensory changes at the T4-T5 level. The patient developed neurological symptoms eight days after the initial onset of COVID-19. An urgent magnetic resonance imaging (MRI) of the spine demonstrated a T2 hyperintense signal extending from C3 to the conus, while cerebrospinal fluid analysis revealed lymphocytosis. Following treatment with high-dose intravenous methylprednisolone, the patient showed significant clinical improvement, with recovery of strength and bladder and bowel function. This case highlights COVID-19 as a possible post-infectious trigger for transverse myelitis and underscores the need to investigate acute urinary retention in young patients.

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Publication Details

Journal
Cureus
Published
2025-12-07
DOI
https://doi.org/10.7759/cureus.98649
Primary Topic
Long-Term Effects of COVID-19
Type
article
Field-Weighted Citation Impact
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article

Post-Infectious Acute Transverse Myelitis in a COVID-19 Patient

Cureus
Long-Term Effects of COVID-19
article

Post-Infectious Acute Transverse Myelitis in a COVID-19 Patient

article en

Abstract

A 41-year-old man with no comorbidities presented with features consistent with a subacute partial upper thoracic myelopathy, two days after treatment in the emergency department for acute urinary retention. On examination, he was ambulatory but had an unsteady gait and lower limb weakness, with brisk reflexes, upgoing plantars, and subtle sensory changes at the T4-T5 level. The patient developed neurological symptoms eight days after the initial onset of COVID-19. An urgent magnetic resonance imaging (MRI) of the spine demonstrated a T2 hyperintense signal extending from C3 to the conus, while cerebrospinal fluid analysis revealed lymphocytosis. Following treatment with high-dose intravenous methylprednisolone, the patient showed significant clinical improvement, with recovery of strength and bladder and bowel function. This case highlights COVID-19 as a possible post-infectious trigger for transverse myelitis and underscores the need to investigate acute urinary retention in young patients.

CureusVol. 17(12)
Princess Alexandra Hospital NHS Trust (GB), Imperial College London (GB)
Good health and well-being
Openalex Percentile: Top 35%
Long-Term Effects of COVID-19
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Post-Infectious Acute Transverse Myelitis in a COVID-19 Patient · Cureus (2025) | TGRS Research Map | TGRS