Apeced's syndrome and lichen planus, is there a causal link? Clinical case and review of the literature (Case report)

Background: Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy syndrome (APECED) is an autosomal recessive disorder characterised by the combination of autoimmune endocrine damage, mucocutaneous candidiasis and ectodermal tissue damage.Case presentation: we report the case of an 18-year-old female patient with APECED syndrome: the abnormalities found are in chronological order: primary hypoparathyroidism, mucocutaneous candidiasis, Addison's disease, Lichen planus, Biermer's anemia and autoimmune ovaritis. Lichen planus was diagnosed clinically and histologically.Conclusion: The occurrence of lichen planus is unusual in this syndrome. In this review, we first review the current knowledge of APECED syndrome and focus on the relationship between APECED syndrome and Lichen planus.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-10-31
DOI
https://doi.org/10.5281/zenodo.17826445
Primary Topic
Adrenal Hormones and Disorders
Type
article
Field-Weighted Citation Impact
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article

Apeced's syndrome and lichen planus, is there a causal link? Clinical case and review of the literature (Case report)

Zenodo (CERN European Organization for Nuclear Research)
Adrenal Hormones and Disorders
article

Apeced's syndrome and lichen planus, is there a causal link? Clinical case and review of the literature (Case report)

article en

Abstract

Background: Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy syndrome (APECED) is an autosomal recessive disorder characterised by the combination of autoimmune endocrine damage, mucocutaneous candidiasis and ectodermal tissue damage.Case presentation: we report the case of an 18-year-old female patient with APECED syndrome: the abnormalities found are in chronological order: primary hypoparathyroidism, mucocutaneous candidiasis, Addison's disease, Lichen planus, Biermer's anemia and autoimmune ovaritis. Lichen planus was diagnosed clinically and histologically.Conclusion: The occurrence of lichen planus is unusual in this syndrome. In this review, we first review the current knowledge of APECED syndrome and focus on the relationship between APECED syndrome and Lichen planus.

Zenodo (CERN European Organization for Nuclear Research)
Université Ibn Zohr (MA)
Good health and well-being
Openalex Percentile: Top 35%
Adrenal Hormones and Disorders
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