Rewiring Speech: rTMS-enabled Recovery in Post-thrombolysis Aphasia

Despite timely thrombolysis, language recovery in post-stroke aphasia is highly variable. We report a patient with severe Broca’s aphasia following a left middle cerebral artery (MCA) infarct whose only verbal output for 6 weeks was the utterance “yani.” Introduction of low-frequency repetitive transcranial magnetic stimulation (rTMS) over the right inferior frontal gyrus, combined with speech-language therapy, led to significant improvements, including production of 3-4-word length sentences with occasional paraphasia. This case highlights how neuromodulation may unlock recovery when conventional therapy alone stalls and provides a way forward. Informed consent was obtained for publication.

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Publication Details

Journal
Journal of Stroke Medicine
Published
2025-12-05
DOI
https://doi.org/10.1177/25166085251400032
Primary Topic
Neurobiology of Language and Bilingualism
Type
article
Field-Weighted Citation Impact
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article

Rewiring Speech: rTMS-enabled Recovery in Post-thrombolysis Aphasia

Journal of Stroke Medicine
Neurobiology of Language and Bilingualism
article

Rewiring Speech: rTMS-enabled Recovery in Post-thrombolysis Aphasia

article en

Abstract

Despite timely thrombolysis, language recovery in post-stroke aphasia is highly variable. We report a patient with severe Broca’s aphasia following a left middle cerebral artery (MCA) infarct whose only verbal output for 6 weeks was the utterance “yani.” Introduction of low-frequency repetitive transcranial magnetic stimulation (rTMS) over the right inferior frontal gyrus, combined with speech-language therapy, led to significant improvements, including production of 3-4-word length sentences with occasional paraphasia. This case highlights how neuromodulation may unlock recovery when conventional therapy alone stalls and provides a way forward. Informed consent was obtained for publication.

Journal of Stroke Medicine
KG Hospital (IN), Joseph Eye Hospital (IN)
Quality Education
Openalex Percentile: Top 39%
Neurobiology of Language and Bilingualism
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