An Unusual Case of Cranial Metastasis Masquerading as Foster Kennedy Syndrome

A 23-year-old male with adenocarcinoma of the rectum presented with sudden and painless loss of vision in his right eye, lasting for a month. Upon examination, there was no perception of light in the right eye along with relative afferent pupillary defect, and the best-corrected visual acuity of the left eye was 6/9p on Snellen’s chart. Fundus examination revealed a pale appearance of the right optic disc and Grade 2 disc edema in the left optic disc. A subsequent magnetic resonance imaging scan showed a space-occupying lesion in the right parietal vault of the skull, as well as an ill-defined sclerotic area in the right zygomatic bone abutting the right optic canal. The presence of a bony metastasis causing increased intracranial pressure but no intracerebral metastasis or direct cerebral mass suggests an atypical presentation of Foster Kennedy syndrome. The patient was then initiated on aggressive chemotherapy and intracranial pressure-lowering agents for management.

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Publication Details

Journal
Delhi Journal of Ophthalmology
Published
2025-10-01
DOI
https://doi.org/10.4103/dljo.dljo_115_24
Primary Topic
Ocular Oncology and Treatments
Type
article
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article

An Unusual Case of Cranial Metastasis Masquerading as Foster Kennedy Syndrome

Delhi Journal of Ophthalmology
Ocular Oncology and Treatments
article

An Unusual Case of Cranial Metastasis Masquerading as Foster Kennedy Syndrome

article en

Abstract

A 23-year-old male with adenocarcinoma of the rectum presented with sudden and painless loss of vision in his right eye, lasting for a month. Upon examination, there was no perception of light in the right eye along with relative afferent pupillary defect, and the best-corrected visual acuity of the left eye was 6/9p on Snellen’s chart. Fundus examination revealed a pale appearance of the right optic disc and Grade 2 disc edema in the left optic disc. A subsequent magnetic resonance imaging scan showed a space-occupying lesion in the right parietal vault of the skull, as well as an ill-defined sclerotic area in the right zygomatic bone abutting the right optic canal. The presence of a bony metastasis causing increased intracranial pressure but no intracerebral metastasis or direct cerebral mass suggests an atypical presentation of Foster Kennedy syndrome. The patient was then initiated on aggressive chemotherapy and intracranial pressure-lowering agents for management.

Delhi Journal of OphthalmologyVol. 35(4)
Safdarjang Hospital (IN)
Good health and well-being
Openalex Percentile: Top 33%
Ocular Oncology and Treatments
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