Retrospective Evaluation of the Incidence, Clinical Characteristics and Outcomes of Gram-Negative Bacterial Infections in Patients with Hematologic Malignancies

In patients with hematologic malignancies, <i>E. coli</i> and <i>Klebsiella</i> spp. remain the predominant pathogens causing bloodstream infections, while persistent bacteremia, ESBL/3GCR, and carbapenem resistance are associated with higher mortality. Notably, carbapenem resistance showed a temporal increase over the study period, underscoring the need for continuous surveillance and timely adaptation of empirical treatment strategies.