PRIMARY PULMONARY HODGKIN'S LYMPHOMA: A CASE OF DIAGNOSTIC COMPLEXITY AND TREATMENT RESISTANCE

Primary pulmonary Hodgkin's lymphoma (PPHL) arises from the lymphoid tissue of the alveolar mucosa or peribronchial lymph nodes. PPHL is extremely rare, representing only 1.5–2.4% of all cases of primary pulmonary lymphoma.[1] Its rarity and nonspecific presentation often lead to diagnostic delays. Symptoms such as cough, fatigue, or chest discomfort mimic other pulmonary diseases, complicating clinical evaluation. Here, we present a case of PPHL initially misdiagnosed as granulomatosis with polyangiitis due to overlapping clinical and histopathological findings. This case emphasizes the importance of a multidisciplinary approach and highlights the critical role of thorough histopathological analysis in establishing an accurate diagnosis.

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Publication Details

Journal
International Journal of Innovative Technologies in Social Science
Published
2025-12-04
DOI
https://doi.org/10.31435/ijitss.4(48).2025.4167
Primary Topic
Lymphoma Diagnosis and Treatment
Type
article
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article

PRIMARY PULMONARY HODGKIN'S LYMPHOMA: A CASE OF DIAGNOSTIC COMPLEXITY AND TREATMENT RESISTANCE

International Journal of Innovative Technologies in Social Science
Lymphoma Diagnosis and Treatment
article

PRIMARY PULMONARY HODGKIN'S LYMPHOMA: A CASE OF DIAGNOSTIC COMPLEXITY AND TREATMENT RESISTANCE

article en

Abstract

Primary pulmonary Hodgkin's lymphoma (PPHL) arises from the lymphoid tissue of the alveolar mucosa or peribronchial lymph nodes. PPHL is extremely rare, representing only 1.5–2.4% of all cases of primary pulmonary lymphoma.[1] Its rarity and nonspecific presentation often lead to diagnostic delays. Symptoms such as cough, fatigue, or chest discomfort mimic other pulmonary diseases, complicating clinical evaluation. Here, we present a case of PPHL initially misdiagnosed as granulomatosis with polyangiitis due to overlapping clinical and histopathological findings. This case emphasizes the importance of a multidisciplinary approach and highlights the critical role of thorough histopathological analysis in establishing an accurate diagnosis.

International Journal of Innovative Technologies in Social Science(4(48))
Medical University of Warsaw (PL), Academy of Business and Health Sciences in Lodz (PL), Université André Salifou (NE), Impact Clean Power Technology (Poland) (PL), Children's Specialized Hospital (US)
Good health and well-being
Openalex Percentile: Top 34%
Lymphoma Diagnosis and Treatment
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