Comparative evaluation of supervised machine learning algorithms for breast cancer prediction using the Wisconsin diagnostic dataset

Breast cancer remains a leading cause of cancer-related mortality among women globally. Early diagnosis is critical to improving survival outcomes, and machine learning (ML) models have shown promise in enhancing predictive accuracy in medical diagnostics. This study presents a comprehensive comparative evaluation of six supervised ML algorithms: Logistic Regression (LR), Random Forest (RF), Support Vector Machine (SVM), K-Nearest Neighbours (KNN), Decision Tree (DT), and Gaussian Naive Bayes (GNB), applied to the Breast Cancer Wisconsin (Diagnostic) dataset. Using RandomForestClassifier for feature importance ranking, SMOTE to address class imbalance, and StandardScaler for normalization, the models were trained and evaluated using an 80-20 train-test split. Performance was assessed based on accuracy, precision, recall, and F1-score. Logistic Regression achieved the highest overall performance (97.90% accuracy, 100% precision). Results indicate that linear models can outperform complex classifiers under well-prepared conditions. This study contributes to ML-aided diagnostics by identifying optimal algorithms for breast cancer prediction using clinical imaging-derived features.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-08-31
DOI
https://doi.org/10.5281/zenodo.17786187
Primary Topic
AI in cancer detection
Type
article
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article

Comparative evaluation of supervised machine learning algorithms for breast cancer prediction using the Wisconsin diagnostic dataset

Zenodo (CERN European Organization for Nuclear Research)
AI in cancer detection
article

Comparative evaluation of supervised machine learning algorithms for breast cancer prediction using the Wisconsin diagnostic dataset

article en

Abstract

Breast cancer remains a leading cause of cancer-related mortality among women globally. Early diagnosis is critical to improving survival outcomes, and machine learning (ML) models have shown promise in enhancing predictive accuracy in medical diagnostics. This study presents a comprehensive comparative evaluation of six supervised ML algorithms: Logistic Regression (LR), Random Forest (RF), Support Vector Machine (SVM), K-Nearest Neighbours (KNN), Decision Tree (DT), and Gaussian Naive Bayes (GNB), applied to the Breast Cancer Wisconsin (Diagnostic) dataset. Using RandomForestClassifier for feature importance ranking, SMOTE to address class imbalance, and StandardScaler for normalization, the models were trained and evaluated using an 80-20 train-test split. Performance was assessed based on accuracy, precision, recall, and F1-score. Logistic Regression achieved the highest overall performance (97.90% accuracy, 100% precision). Results indicate that linear models can outperform complex classifiers under well-prepared conditions. This study contributes to ML-aided diagnostics by identifying optimal algorithms for breast cancer prediction using clinical imaging-derived features.

Zenodo (CERN European Organization for Nuclear Research)
The Federal Polytechnic, Ado-Ekiti (NG)
Good health and well-being
Openalex Percentile: Top 21%
AI in cancer detection
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