The effect of safranal on anxiety and the MYD88/NF-kb signaling pathway in the hippocampus in a rat model of ulcerative colitis

These findings suggest that safranal exerts anxiolytic effects in experimental colitis, likely mediated through downregulation of the TLR4/MYD88/NF-κB pathway and reduced hippocampal neuroinflammation.

Institutions

Shahid Chamran University of Ahvaz (IR)

Publication Details

Journal: Current Research in Physiology
Published: 2025-11-28
DOI: https://doi.org/10.1016/j.crphys.2025.100177
Primary Topic: Saffron Plant Research Studies
Type: article
Field-Weighted Citation Impact: 0.00

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article

The effect of safranal on anxiety and the MYD88/NF-kb signaling pathway in the hippocampus in a rat model of ulcerative colitis

Nov 28, 2025

Current Research in Physiology

Saffron Plant Research Studies

article

The effect of safranal on anxiety and the MYD88/NF-kb signaling pathway in the hippocampus in a rat model of ulcerative colitis

November 28, 2025article en

Abstract

Current Research in PhysiologyVol. 9

Shahid Chamran University of Ahvaz (IR)

Good health and well-being

Openalex Percentile: Top 35%

Saffron Plant Research Studies

DOI Open Access PDF OpenAlex

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The effect of safranal on anxiety and the MYD88/NF-kb signaling pathway in the hippocampus in a rat model of ulcerative colitis · Current Research in Physiology (2025) | TGRS Research Map | TGRS