A rare case report of unusual presentation of jejunal gastro intestinal stromal tumor

• An Unusual presentation of small intestinal GIST • A mass arising from antimesenteric border of jejunum and was adherent to greater omentum above and lateral peritoneal wall inferiorly • Treatment provided was the complete resection of the mass with post operative chemotherapy with imatinib was started. Gastro intestinal stromal tumours (GIST) are benign to malignant mesenchymal tumours comprising ∼1% of GI malignancies. They are soft tissue sarcomas most commonly arising from GI system. [1–3] Most common site being stomach and rarely arise from other parts of intestines. We present a case of a 49 year old male patient diagnosed with jejunal GIST presented with urinary complaints, and found to have painless abdominal lump which was mobile. Radiological investigations were showing right iliac fossa mass. On surgical exploration, we found a mass arising from antimesenteric border of jejunum and was adherent to greater omentum above and lateral peritoneal wall inferiorly. Complete resection of the tumour with Jejuno-jejunal anastomosis was performed. Histopathology of the excised tumour also confirmed the diagnosis of GIST. GIST commonly found in stomach and rarely in various parts of GI system. Treatment depends on tumour size, type and location. Complete resection followed by chemotherapy if required, is the mainstay of treatment. A GIST can also be considered as a differential diagnosis for abdominal s symptoms which has various presentation and outcome based upon the type and attachment to nearby structures. Surgical resection remains the initial part of management.

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Publication Details

Journal
Current Problems in Cancer Case Reports
Published
2025-11-27
DOI
https://doi.org/10.1016/j.cpccr.2025.100397
Primary Topic
Gastrointestinal Tumor Research and Treatment
Type
article
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A rare case report of unusual presentation of jejunal gastro intestinal stromal tumor

Current Problems in Cancer Case Reports
Gastrointestinal Tumor Research and Treatment
article

A rare case report of unusual presentation of jejunal gastro intestinal stromal tumor

article en

Abstract

• An Unusual presentation of small intestinal GIST • A mass arising from antimesenteric border of jejunum and was adherent to greater omentum above and lateral peritoneal wall inferiorly • Treatment provided was the complete resection of the mass with post operative chemotherapy with imatinib was started. Gastro intestinal stromal tumours (GIST) are benign to malignant mesenchymal tumours comprising ∼1% of GI malignancies. They are soft tissue sarcomas most commonly arising from GI system. [1–3] Most common site being stomach and rarely arise from other parts of intestines. We present a case of a 49 year old male patient diagnosed with jejunal GIST presented with urinary complaints, and found to have painless abdominal lump which was mobile. Radiological investigations were showing right iliac fossa mass. On surgical exploration, we found a mass arising from antimesenteric border of jejunum and was adherent to greater omentum above and lateral peritoneal wall inferiorly. Complete resection of the tumour with Jejuno-jejunal anastomosis was performed. Histopathology of the excised tumour also confirmed the diagnosis of GIST. GIST commonly found in stomach and rarely in various parts of GI system. Treatment depends on tumour size, type and location. Complete resection followed by chemotherapy if required, is the mainstay of treatment. A GIST can also be considered as a differential diagnosis for abdominal s symptoms which has various presentation and outcome based upon the type and attachment to nearby structures. Surgical resection remains the initial part of management.

Current Problems in Cancer Case ReportsVol. 20
Krishna Institute of Medical Sciences (IN), Krishna Institute of Medical Sciences Deemed University (IN)
Good health and well-being
Openalex Percentile: Top 34%
Gastrointestinal Tumor Research and Treatment
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A rare case report of unusual presentation of jejunal gastro intestinal stromal tumor · Current Problems in Cancer Case Reports (2025) | TGRS Research Map | TGRS