To Study Of Efficacy Of Malati – Madhuka Gel On Garbhini Kikkisa (Straie Gravidarum)

Striae gravidarum (SG), commonly known as stretch marks, affect up to 90% of pregnant women, often causingcosmetic and psychological distress. Ayurveda identifies this condition as Garbhini Kikkisa, a Tridoshaja disordercharacterized by kandu (itching), daha (burning), and vaivarnya (discoloration). Despite being medically harmless,Striae gravidarum (impairs quality of life, prompting the need for safe, effective, and economical therapies duringpregnancy. To evaluate the clinical efficacy and safety of a gel formulation containing Malati (Jasminum officinale)and Madhuka (Glycyrrhiza glabra) in the management of Garbhini Kikkisa. An open-label, prospective clinicalstudy was conducted on 33 antenatal women between 21–30 years of age in the 2nd or 3rd trimester presentingwith Kikkisa. Malati–Madhuka Gel was applied twice daily for 4 weeks. Assessment was made on subjectiveparameters (kandu, daha, vaivarnya) and objective measures (scar grading, Davey’s scoring for striae distribution).Data were analyzed using the Wilcoxon signed-rank test. The formulation produced complete relief in itching (100%)and burning sensation (100%), along with 60% improvement in discoloration. However, only 22.85% improvementwas observed in scar length and depth. The gel was well tolerated, with no adverse events reported. Malati–MadhukaGel is highly effective in alleviating the symptomatic aspects of Kikkisa, though its impact on structural striaereduction is limited. The formulation is safe, economical, and suitable for use during pregnancy. Larger randomizedcontrolled trials are recommended.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-03-23
DOI
https://doi.org/10.5281/zenodo.17685693
Primary Topic
Dermatologic Treatments and Research
Type
article
Field-Weighted Citation Impact
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article

To Study Of Efficacy Of Malati – Madhuka Gel On Garbhini Kikkisa (Straie Gravidarum)

Zenodo (CERN European Organization for Nuclear Research)
Dermatologic Treatments and Research
article

To Study Of Efficacy Of Malati – Madhuka Gel On Garbhini Kikkisa (Straie Gravidarum)

article en

Abstract

Striae gravidarum (SG), commonly known as stretch marks, affect up to 90% of pregnant women, often causingcosmetic and psychological distress. Ayurveda identifies this condition as Garbhini Kikkisa, a Tridoshaja disordercharacterized by kandu (itching), daha (burning), and vaivarnya (discoloration). Despite being medically harmless,Striae gravidarum (impairs quality of life, prompting the need for safe, effective, and economical therapies duringpregnancy. To evaluate the clinical efficacy and safety of a gel formulation containing Malati (Jasminum officinale)and Madhuka (Glycyrrhiza glabra) in the management of Garbhini Kikkisa. An open-label, prospective clinicalstudy was conducted on 33 antenatal women between 21–30 years of age in the 2nd or 3rd trimester presentingwith Kikkisa. Malati–Madhuka Gel was applied twice daily for 4 weeks. Assessment was made on subjectiveparameters (kandu, daha, vaivarnya) and objective measures (scar grading, Davey’s scoring for striae distribution).Data were analyzed using the Wilcoxon signed-rank test. The formulation produced complete relief in itching (100%)and burning sensation (100%), along with 60% improvement in discoloration. However, only 22.85% improvementwas observed in scar length and depth. The gel was well tolerated, with no adverse events reported. Malati–MadhukaGel is highly effective in alleviating the symptomatic aspects of Kikkisa, though its impact on structural striaereduction is limited. The formulation is safe, economical, and suitable for use during pregnancy. Larger randomizedcontrolled trials are recommended.

Zenodo (CERN European Organization for Nuclear Research)
Bharati Vidyapeeth (Deemed to be University) (IN)
Openalex Percentile: Top 28%
Dermatologic Treatments and Research
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To Study Of Efficacy Of Malati – Madhuka Gel On Garbhini Kikkisa (Straie Gravidarum) · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS