Mitigation of Aβ neurotoxicity in Alzheimer's disease using a non-toxic platinum complex derived from retinamide
A retinamide–platinum complex (RP) inhibits self- and metal-induced Aβ42 aggregation, reduces the generation of ROS, prevents neuroinflammation and neuronal impairment, and relieves the Aβ42-induced neurotoxicity in the AD model organism C. elegans .
Institutions
- Nanjing University (CN)
Publication Details
- Journal
- Inorganic Chemistry Frontiers
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1039/d5qi01746g
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00