Enhanced Risk Prediction for Coronary Heart Disease by Leveraging Polygenic Risk Score and Clinical Risk Score in European Hypertensive Adults

Compared to the clinical risk score, integrating the PRS significantly improved CHD prediction and better identified CHD risk trajectories, especially in the European hypertensive adult population.

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Publication Details

Journal
Journal of Cardiovascular Development and Disease
Published
2025-11-24
DOI
https://doi.org/10.3390/jcdd12120454
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Enhanced Risk Prediction for Coronary Heart Disease by Leveraging Polygenic Risk Score and Clinical Risk Score in European Hypertensive Adults

Journal of Cardiovascular Development and Disease
Genetic Associations and Epidemiology
article

Enhanced Risk Prediction for Coronary Heart Disease by Leveraging Polygenic Risk Score and Clinical Risk Score in European Hypertensive Adults

article en

Abstract

Compared to the clinical risk score, integrating the PRS significantly improved CHD prediction and better identified CHD risk trajectories, especially in the European hypertensive adult population.

Journal of Cardiovascular Development and DiseaseVol. 12(12)
Fudan University (CN)
Good health and well-being
Openalex Percentile: Top 31%
Genetic Associations and Epidemiology
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Enhanced Risk Prediction for Coronary Heart Disease by Leveraging Polygenic Risk Score and Clinical Risk Score in European Hypertensive Adults · Journal of Cardiovascular Development and Disease (2025) | TGRS Research Map | TGRS