New-Onset Gambling Addiction Following Treatment for Psychosis With Cariprazine

Cariprazine is an atypical antipsychotic primarily used to treat schizophrenia and bipolar I disorder. Unlike most antipsychotics, it is effective in managing both the positive and negative symptoms of schizophrenia. However, it has recently been associated with impulse control disorders (ICDs) as a potential side effect. This case report describes a 42-year-old female patient with schizoaffective disorder who developed new-onset compulsive gambling following initiation of cariprazine therapy, despite well-controlled psychotic symptoms. After discontinuing cariprazine, the patient experienced a notable improvement in impulse control with complete cessation of gambling behavior. This report highlights the importance of careful monitoring for such side effects in patients receiving cariprazine and, to our knowledge, is the first to describe compulsive gambling associated with this medication.