Foreign Body Giant Cell Reaction with Multi Drug Resistance to Anaerobic Bacteria in Maxillofacial Region: An Unusual Case Report

Foreign Body Giant Cells (FBGCs) are most commonly observed at the tissue/material interface, where the size of foreign particulate is too large to permit macrophage phagocytosis. The insertion of foreign bodies into human oral and perioral tissues may originate from traumatic events, postoperative dental procedures. When the infection caused by Pseudomonas aeruginosa occurs in these conditions, it can result in life-threatening conditions due to its variable antibiotic resistance, and the treatment is questionable. Here, we report a case of FBGC reaction with multidrug resistance in a 35-year-old female patient postoperatively, who has undergone Open Reduction and Internal Fixation (ORIF) under general anaesthesia for midfacial fracture.

Publication Details

Journal
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Published
2025-11-22
DOI
https://doi.org/10.7860/jcdr/2026/79488.22259
Primary Topic
Orthopedic Infections and Treatments
Type
article
Field-Weighted Citation Impact
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article

Foreign Body Giant Cell Reaction with Multi Drug Resistance to Anaerobic Bacteria in Maxillofacial Region: An Unusual Case Report

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Orthopedic Infections and Treatments
article

Foreign Body Giant Cell Reaction with Multi Drug Resistance to Anaerobic Bacteria in Maxillofacial Region: An Unusual Case Report

article en

Abstract

Foreign Body Giant Cells (FBGCs) are most commonly observed at the tissue/material interface, where the size of foreign particulate is too large to permit macrophage phagocytosis. The insertion of foreign bodies into human oral and perioral tissues may originate from traumatic events, postoperative dental procedures. When the infection caused by Pseudomonas aeruginosa occurs in these conditions, it can result in life-threatening conditions due to its variable antibiotic resistance, and the treatment is questionable. Here, we report a case of FBGC reaction with multidrug resistance in a 35-year-old female patient postoperatively, who has undergone Open Reduction and Internal Fixation (ORIF) under general anaesthesia for midfacial fracture.

JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
Gender equality
Openalex Percentile: Top 31%
Orthopedic Infections and Treatments
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