EFFICACY AND SAFETY OF MELINE® TREAT MENTS IN PATIENTS WITH PERIOCULAR HYPERPIGMENTATION

ABSTRACT This study evaluated the efficacy and safety of MeLine® treatments in patients with periocular hyperpigmentation, a condition that affects quality of life by altering aesthetic perception. A prospective, observational, and quantitative study was conducted, analyzing 52 patients between January 2023 and March 2024. Inclusion criteria considered adults aged 25 to 45 years with no recent treatments for dark circles. The treatment included microexfoliation with Kojic Acid, Gingko Biloba Extract, Tranexamic Acid, Lactobionic Acid, Ruscus Aculeatus, Troxerutin, and Melilotus Officinalis. Results showed that 92% of patients reported combined benefits such as brighter skin and reduction of wrinkles. Although 30% experienced adverse effects, these were manageable. A significant correlation was found between satisfaction with the lightening of dark circles and other perceived benefits, including improvements in skin texture. Despite the high cost of treatment, patients showed high levels of overall satisfaction and willingness to recommend it. Treatment with MeLine® proved to be an effective option for periocular hyperpigmentation, yielding positive aesthetic and psychological results. However, further research is recommended to validate its use in different dermatological contexts.