REVIEW ON ROLE OF TINOSPORA CORDIFOLIA AND ZINGIBER OFFICINALE IN AMAVATA (RHEUMATOID ARTHRITIS)

Amavata is a term derived from words Ama & Vata. Derangement of Agni is the main cause for this disease which results in the production of Ama. The entity ama is a disease in which the body's many disorders have a poisonous effect. When ama gets circulated in the body with the vitiated vata dosha, it occupies the shleshma sthana in the body particularly sandhis i.e joints which results in the formation of painful disease Amavata. Amavata's clinical manifestations are strikingly similar to a specific type of rheumatological condition known as Rheumatoid Arthritis, which is a chronic, progressive, auto-immune, inflammatory disease with clinical features like pain, stiffness, swelling, redness over synovial joints in the body and some other extra-articular menifestations. The disease Amavata is mentioned in Ayurveda since the era of Madhavakara (16th Century A.D.) under the category of Vatakaphaja vikaras. Viruddhahara, Mandagni, Exercise after a large meal, and other Amavata hetus are told by Madhavkara. Ama being the main causative factor for pathogenesis of the disease, the treatment regimen described in Ayurveda includes Langhan, Swedan, deepana, pachana, Virechan, Basti etc. Ayurvedic herbal medicines include anti-inflammatory and immunomodulatory properties that may be effective and appropriate for the treatment of Amavata. Tikta, Kashaya Rasa, Madhur Vipak, and Ushana Veerya are all found in Guduchi, as well as the dual effect of and Bruhana and Vata shamana on the tissues, particularly the Asthi Dhatu. It is also used for immunomodulatory and anti-inflammatory actions. Sunthi possess katu rasa, laghu and snighdha guna, ushna veerya and madhura vipaka and is kapha and vata shamaka. It also has best deepana and pachana properties. So, the present study deals with systemic review of role of Tinospora cordifolia (Guduchi) and Zingiber officinale (Sunthi) in Amavata.