AN ILLUSTRATED CLINICAL STUDY & THERAPEUTICS RESPONSES OF UNANI FORMULATION IN INDUCTION OF OVULATION (TASHJEE-E-BAIZA / BAIZA AWARI)- A RANDOMIZED CONTROLLED STUDY

Infertility, known as Uqr in Unani medicine, remains a significant reproductive health issue, with anovulation being one of its leading causes. Ovulation induction plays a crucial role in the management of anovulatory infertility, and the Unani system of medicine offers effective, natural, and safe approaches for restoring ovulation through Muwallid-e-Mani (ovulation-inducing) and Muqawwi-e-Rahem (uterine strengthening) drugs. This study aimed to evaluate the clinical efficacy of selected Unani formulations in the induction of ovulation and management of female infertility due to anovulatory cycles, while minimizing the side effects commonly associated with conventional hormonal therapies. A randomized controlled clinical study was conducted on 40 female patients aged 20–40 years, diagnosed with anovulatory infertility, at Nizamia General Hospital, Hyderabad. Group A: Received Saleb Mesri (Orchis mascula), Tukhm-e-Gazar (Daucus carota), Kaiphal (Myrica nagi), Tudari Surkh (Matthiola incana) orally, along with Roghan-e-Chambeli (Jasminum grandiflorum) and Safaidi Beiza-e-Murgh (egg white) as Humool (pessary) for 5 days per cycle. Group B: Received Bahman Sufaid (Centaurea behen), Inderjow Shereen (Wrightia tinctoria), Ushba Daisi (Hemidesmus indicus), and Khand Siyah (jaggery) orally for 10 days per cycle. Treatment continued for three consecutive menstrual cycles, with ultrasonographic follicular monitoring to assess ovulation and conception outcomes. In Group A, ovulation occurred in 95% of cases, with conception in 5% after the first cycle, 45% after the second cycle, and 15% after the third cycle. Group B showed 75% ovulatory response, with 10% conception in the first cycle, 25% in the second, and 10% in the third, while 15% remained anovulatory. Improvement in endometrial thickness and follicular development was observed in both groups, particularly in Group A. The study confirms that Unani formulations effectively induce ovulation and enhance fertility potential in women with anovulatory cycles, primarily through their aphrodisiac, hormonal, deobstruent, uterine tonic, and nutritive actions.