Lipid Keratopathy: A Case Report

Lipid keratopathy is a rare corneal disorder characterized by the deposition of lipid material within the corneal stroma, leading progressively to opacification and visual impairment. This condition may occur secondary to ocular diseases such as chronic inflammation, trauma, neovascularization, or infections, but it can also be associated with systemic lipid metabolism abnormalities. In some cases, however, it arises without any identifiable predisposing factor and is classified as idiopathic. We report the case of a 47-year-old woman who presented to our ophthalmology department with progressive corneal opacification. Clinical examination revealed stromal lipid deposits consistent with lipid keratopathy, in the absence of prior ocular pathology or systemic disease, highlighting the importance of considering idiopathic forms in the differential diagnosis.