APPLIED PHYSIOLOGICAL PRINCIPLES OF VANDHYATVA IN AYURVEDA: AN INTEGRATIVE CRITICAL ANALYSIS

Background: Infertility affects approximately 15% of couples globally, representing a significant reproductive health challenge. Ayurveda provides distinctive physiological perspectives on reproductive function through concepts of Shukra dhatu, Artava, Tridosha, and Garbha sambhava sharir. Objective: This review critically examines applied physiological foundations of Ayurvedic infertility management, correlates traditional frameworks with contemporary reproductive biology, and evaluates clinical evidence supporting therapeutic interventions. Methods: Comprehensive literature search was conducted across PubMed, Scopus, and Web of Science databases alongside classical Ayurvedic texts including Charaka Samhita, Sushruta Samhita, and Ashtanga Hridaya for publications from 1990-2025. Results: Ayurvedic reproductive physiology conceptualizes fertility through integrated systems involving Dhatus, Doshas, Agni, and Srotas. Vajikarana herbs including Withania somnifera, Asparagus racemosus, Mucuna pruriens, and Tribulus terrestris exhibit multifaceted effectson hypothalamic-pituitary-gonadal axis regulation, steroidogenesis, and gametogenesis. Clinical studies demonstrate improvements in semen parameters, menstrual regularity, and pregnancy outcomes. Conclusion: Ayurvedic medicine offers comprehensive individualized frameworks for reproductive dysfunction management. Evidence-based integration with modern reproductive medicine presents promising opportunities for personalized approaches.