Determining the Difference Between the Chronological and Biological Age of Athletes Diagnosed with Trigeminal Neuralgia

Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by highly variable symptoms that may fluctuate within a single day. Individuals diagnosed with MS experience changes in both functional and cognitive capacities, necessitating continuous adjustments in lifestyle and physical activity. Within a fitness context, the use of resistance bands and training aids such as stationary bicycles or ergometers enables safe, adapted exercise on days when symptoms are stable. However, the primary goal of physical activity in the context of MS is to establish a sustainable form of movement that remains feasible even in the presence of symptoms. This research applied inferential statistical analysis using Spearman’s rank-order correlation to assess the relationships between variables, resulting in a correlation matrix with Spearman's rho values and corresponding p-values. Findings indicate positive effects of regular physical activity in mitigating MS symptoms such as fatigue, mobility difficulties, and cognitive impairments. Beyond physical benefits, exercise contributes to a greater sense of control over the disease and enhances social and emotional well-being. A specific feature of this study is its focus on individuals living on the Dalmatian coast, where climatic factorsespecially elevated temperatures for most of the year—further influence exercise adaptations, particularly due to the common occurrence of heat intolerance in people with MS. Accordingly, the importance of a personalized exercise approach is emphasized, aligned with current recommendations from the National MS Society (USA), which include physical activity guidelines tailored to all levels of functional ability.