Chronic Pancreatitis Presenting with Portal Vein Thrombosis in a Child - A Case Report

Background: Peripancreatic vascular complications have been reported with both acute and chronic pancreatitis (CP), but mainly in adults. Clinical Description: A 3-year-old girl was admitted with complaints of gradual onset abdominal distension and low-grade fever for few months, associated with severe upper abdominal pain. Examination revealed short stature with marked pallor, along with hepatosplenomegaly. Management and Outcome: The child was diagnosed as a CP on the basis of abdominal pain, increased lipase 3 times above the upper range, and calcified lesions in the pancreas in ultrasonography (USG) (INSPIRE Criteria). USG color Doppler confirmed portal vein thrombosis, with decreased blood flow in the portal vein. The child was provided supportive care along with subcutaneous enoxaparin at 1 mg/kg, 12 hourly. At follow-up after 1.5 months, the child was asymptomatic, and USG Doppler showed the absence of thrombus, and enoxaparin was stopped. Conclusion: The case described here creates awareness regarding the rare occurrence of portal vein thrombosis causing extrahepatic portal hypertension in children with CP.

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Publication Details

Journal
Indian Pediatrics Case Reports
Published
2025-10-01
DOI
https://doi.org/10.4103/ipcares.ipcares_126_25
Primary Topic
Pancreatitis Pathology and Treatment
Type
article
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article

Chronic Pancreatitis Presenting with Portal Vein Thrombosis in a Child - A Case Report

Indian Pediatrics Case Reports
Pancreatitis Pathology and Treatment
article

Chronic Pancreatitis Presenting with Portal Vein Thrombosis in a Child - A Case Report

article en

Abstract

Background: Peripancreatic vascular complications have been reported with both acute and chronic pancreatitis (CP), but mainly in adults. Clinical Description: A 3-year-old girl was admitted with complaints of gradual onset abdominal distension and low-grade fever for few months, associated with severe upper abdominal pain. Examination revealed short stature with marked pallor, along with hepatosplenomegaly. Management and Outcome: The child was diagnosed as a CP on the basis of abdominal pain, increased lipase 3 times above the upper range, and calcified lesions in the pancreas in ultrasonography (USG) (INSPIRE Criteria). USG color Doppler confirmed portal vein thrombosis, with decreased blood flow in the portal vein. The child was provided supportive care along with subcutaneous enoxaparin at 1 mg/kg, 12 hourly. At follow-up after 1.5 months, the child was asymptomatic, and USG Doppler showed the absence of thrombus, and enoxaparin was stopped. Conclusion: The case described here creates awareness regarding the rare occurrence of portal vein thrombosis causing extrahepatic portal hypertension in children with CP.

Indian Pediatrics Case ReportsVol. 5(4)
Mahatma Gandhi Memorial Medical College (IN)
Good health and well-being
Openalex Percentile: Top 31%
Pancreatitis Pathology and Treatment
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Chronic Pancreatitis Presenting with Portal Vein Thrombosis in a Child - A Case Report · Indian Pediatrics Case Reports (2025) | TGRS Research Map | TGRS